Journal Information

Articles in press

Articles in press are accepted, peer reviewed articles that are not yet assigned to volumes/issues, but are citable using DOI. More info

Rapid maxillary expansion in pediatric patients with obstructive sleep apnea: an umbrella review
Denise Fernandes Barbosa, Laura Fernandes Bana, Maria Cristina Buta Michel, Miguel Meira e Cruz, Edilson Zancanella, Almiro José Machado Júnior

  • The studies of rapid maxillary expansion in obstructive sleep apnea children's treatment are based on low-quality evidence.

  • Management decisions should be linked to the phenotype, considering outcomes beyond the apnea-hypopnea index.

  • A health policy is needed focusing on respiratory disorders prevention.

Open access
Available online 8 March 2023
Combination of Merocel sponge with Lipopolysaccharide to establish rat rhinosinusitis model
Mengmeng Sun, Junjie Yang, Jiayu Liu, Ming Jing, Leiming Zhang, Wenyu Xin

  • For the first time, a rat rhinosinusitis model was established using LPS and Merocel sponge.

  • LPS can induce nasal inflammation through TLR4 signaling pathway.

  • LPS can reduce AQP5, occludin protein expression.

Open access
Available online 2 March 2023
Prognostic and predictive role of soluble programmed death ligand-1 in head and neck cancer
Maria Molga-Magusiak, Anna Rzepakowska, Michał Żurek, Iwona Kotuła, Urszula Demkow, Kazimierz Niemczyk

  • sPD-L1 is potential predictive biomarker for differentiation of malignant lesions in head and neck region.

  • Significantly higher levels of sPD-L1 are detected in malignant tumors.

  • Higher levels of sPD-L1 proves reliable prognostic biomarker in predicting early recurrence of laryngeal cancer.

  • Increased sPD-L1 correlates with poor disease-free survival in head and neck cancer.

Open access
Available online 2 March 2023
Effect of tinnitus on sound localization ability in patients with normal hearing
Yue Long, Wei Wang, Jiao Liu, Ke Liu, Shusheng Gong

  • Tinnitus is a common disorder that affects hearing and social interactions.

  • Patients with tinnitus have reported hearing difficulties in noisy environments.

  • Tinnitus negatively impacts sound source localization in those with normal hearing.

  • It might also affect the processing of brain cues for sound source discrimination.

Open access
Available online 24 February 2023
The development of nasal polyps involves early middle meatus mucous remodeling via TGF-β1 mediated PAI-1 reduction
Yijun Liu, Longlan Shu, Xiaocong Jiang, Yue Zhang, Qian Chen, Yang Shen, Yucheng Yang

  • We have investigated the fibrosis genes in the TGF-β pathway in the early and mature nasal polyps development process, respectively.

  • PAI-1 is involved in early nasal polyps, and its low fibrolysis is predisposed to nasal polyps’ development.

  • PAI-1 is affected by the TGF pathway, and low PAI-1 expression is one of the main reasons for tissue remodeling in nasal polyps.

Open access
Available online 24 February 2023
Associated oral manifestations with HIV southeastern Brazilian patients on antiretroviral therapy
Brisa Ketrine Lustosa de Souza, Daniele Sorgatto Faé, Cleidiel Aparecido Araújo Lemos, Francielle Silvestre Verner, Renato Assis Machado, Rose Mara Ortega, Sibele Nascimento de Aquino

  • The associated oral manifestations in HIV patients remain present even in the HAART era.

  • Periodontal disease with or without mobility were the predominant oral lesions in the patients of this study.

  • No relationship was found between oral lesions, TCD4+ and TCD8+ cell count, TCD4:TCD8 ratio, or viral load.

  • There is a protective effect of duration of treatment with relation to periodontal disease with mobility.

Open access
Available online 21 February 2023
Changes in brain gray matter volume in nasopharyngeal carcinoma patients after radiotherapy in long-term follow-up
Wenjia Zhu, Fu Chen, Dongming Yin, Keguang Chen, Shengzi Wang

  • The change in brain gray matter volume in NPC patients after radiotherapy in long-term follow-up were studied.

  • NPC patients with the radiation-induced hearing loss had abnormal brain gray matter volume in the auditory center and other sensory centers.

  • Our findings might provide new understanding into the pathogenesis of radiation-induced brain damage in normal-appearing brain tissue.

Open access
Available online 19 February 2023
Transcutaneous injection of triamcinolone acetonide for persistent glottic granulation after laser microsurgery
Ying Zhang, Shisheng Li

  • Persistent granulation could not disappear after conservative treatment.

  • Reoperation was not recommended.

  • Triamcinolone Acetonide (TA) injection in vocal fold is mature.

  • TA could accelerate the disappear of granulation or persistent granulation.

  • Suitable for huge granulation which blocks the glottis and the recur.

Open access
Available online 19 February 2023
Impact of the COVID-19 Pandemic on Brazilian Head and Neck Surgery Centers
Gustavo Fernandes de Alvarenga, Ana Kober Nogueira Leite, Carlos Neutzling Lehn, Rogério Aparecido Dedivitis, Marianne Yumi Nakai, Beatriz Godoi Cavalheiro, Gilberto Vaz Teixeira, Rafael De Cicco, Luiz Paulo Kowalski, Leandro Luongo de Matos

  • The total number of diagnostic exams and surgical procedures had decreased significantly.

  • Surgery for head and neck cancer treatment increased in the total surgical logbook.

  • Most residents faced reduction in surgical logbook and deployment to COVID-19 facilities.

Open access
Available online 16 February 2023
Algorithm for pediatric orbital blowout fractures: a 20-year retrospective cohort study
Kosuke Takabayashi, Yohei Maeda, Nobuya Kataoka, Hiroyuki Kagokawad, Masayoshi Nagaminea, Isao Otad, Taketoshi Fujita

  • Develop a treatment algorithm for pediatric orbital blowout fractures.

  • Findings to consider urgent release for linear type of pediatric orbital blowout fractures: missing rectus and OCR.

  • Present the results using the Hess area ratio, an objective measure of treatment outcome.

  • Simple algorithm easily used even for physicians who do not specialize in orbital care.

  • Algorithm producing successful treatment outcomes.

Open access
Available online 7 February 2023
Brazilian Journal of Otorhinolaryngology (English Edition)

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Articles submitted as of May 1, 2022, which are accepted for publication will be subject to a fee (Article Publishing Charge, APC) payment by the author or research funder to cover the costs associated with publication. By submitting the manuscript to this journal, the authors agree to these terms. All manuscripts must be submitted in English.. Os artigos submetidos a partir de 1º de maio de 2022, que forem aceitos para publicação estarão sujeitos a uma taxa (Article Publishing Charge, APC) a ser paga pelo autor para cobrir os custos associados à publicação. Ao submeterem o manuscrito a esta revista, os autores concordam com esses termos. Todos os manuscritos devem ser submetidos em inglês.