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Vol. 88. Issue S2.
Pages 16 (November - December 2022)
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Vol. 88. Issue S2.
Pages 16 (November - December 2022)
Open Access
Efficacy of injectable substances in the treatment of glottic insufficiency: A systematic review
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Renato Battistel Santana
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renato_battistel@hotmail.com

Corresponding author.
, Regina Helena Garcia Martins, José Paulo Pinotti Ferreira Junior, Débora Pereira Henriques, Antonio Jose Maria Catâneo, Isabella Gonçalves Pierri, Alexandre Palaro Braga, Neemias Santos Carneiro
Departamento de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Universidade Estadual Paulista “Júlio de Mesquita Filho” (Unesp), Botucatu, SP, Brazil
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Objectives: To evaluate, through a systematic review, the results of glottic insufficiency treatments with the two most used injectable substances (hyaluronic acid or hydroxyapatite).

Methods: The question is whether injectable substances (hyaluronic acid or hydroxyapatite) are effective in treating patients with glottic incompetence. As criteria for inclusion of studies for this review, studies evaluating the function of the vocal folds before and after one and six months of injection of injectable substances (hyaluronic acid or hydroxyapatite), adult patient with atrophy, scars and unilateral paralysis of the vocal folds with glottic incompetence. The intervention was the use of treatments with injectable drugs (hyaluronic acid or hydroxyapatite). Control was established with adult patients with atrophy, scars and unilateral paralysis of the vocal folds with glottic incompetence, before intervênção. As outcomes, the reduction of the score in the vocal handicap index questionnaire, reduction of the scores of the auditory-perceptual evaluation of the voice by the GRBAS scale and increase in the values of the maximum phonation time were evaluated.

Results/conclusion: Both injectable substances, hydroxyapatite or hyaluronic acid, proved to be effective in the treatment of glottic incompetence.

Keywords: Glottic insuficiency; Larynx; Voice; Fillers; Vocal fold.

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Brazilian Journal of Otorhinolaryngology (English Edition)
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