Journal Information

Last published articles

Review article
Cochlear implantation in vestibular schwannoma: A game changer? A narrative review
Luis Lassaletta, Miryam Calvino, Isabel Sánchez-Cuadrado, José Manuel Morales-Puebla, Javier Gavilán
Highlights

  • Cochlear implantation is a solution for some patients with vestibular schwannoma.

  • Audiological outcomes are variable, but worse than conventional CI candidates.

  • Cochlear implantation can be performed in operated, observed or irradiated cases.

  • The Auditory Nerve Test System is a useful intraoperative tool.

  • A positive wave V elicited with the ANTS strongly predicts at least sound detection.

Full text access
Review article
Application of an active middle ear implant in congenital middle ear malformations: A contemporary review
Vagner Antonio Rodrigues da Silva, Henrique Furlan Pauna, Guilherme Correa Guimarães, Joel Lavinsky, Thomas E. Linder, Arthur Menino Castilho
Highlights

  • External ear malformations frequently lead to conductive hearing loss.

  • The Jahrsdoerfer score is used to qualify patients for corrective surgery.

  • Patients presented improvement of bone and air-conduction thresholds.

Full text access
Original Article
Concentrated growth factors promote epithelization in the mastoid obliteration after canal wall down mastoidectomy
Mengyi Liu, Lue Zhang, Quanming Zhang, Nan Zeng, Shuo Li, Shuyue Guo, Yaqin Zhao, Mingxing Tang, Qiong Yang
Highlights

  • Large mastoid cavity after CWD mastoidectomy should be obliterated properly.

  • HA particles used for cavity obliteration should be properly covered.

  • CGF promotes complete epithelialization of the mastoid cavity.

Full text access
Original article
The important role of cuproptosis and cuproptosis-related genes in the development of thyroid carcinoma revealed by transcriptomic analysis and experiments
Yani Liu, Yanyan He, Shizhen Lei
Highlights

  • Cuproptosis was the most enriched type of Programmed Cell Death (PCD) processes in THCA.

  • Cuproptosis was associated with tumor malignancy of THCA.

  • A cuproptosis-related gene, CDKN2A, was upregulated in THCA sample.

  • CDKN2A was associated with poor prognosis and TME in THCA.

Full text access
Original article
LAMB1 promotes proliferation and metastasis in nasopharyngeal carcinoma and shapes the immune-suppressive tumor microenvironment
Enzi Feng, Xinyu Yang, Jie Yang, Qianqian Qu, Xiaojiang Li
Highlights

  • NPC exhibits significantly elevated expression of LAMB1.

  • LAMB1 plays immune-suppressive role in NPC.

  • LAMB1 promotes NPC cells proliferation, invasion and migration.

Full text access
Review article
Cochlear implantation and cognitive function in the older adult population: current state of the art and future perspectives
Tinne Vandenbroeke, Ellen Andries, Marc J.W. Lammers, Anouk Hofkens-Van den Brandt, Griet Mertens, Vincent Van Rompaey
Highlights

  • Use of cochlear implants can attenuate cognitive decline in adults with hearing loss.

  • The cognitive test should be adapted for individuals with hearing loss.

  • Evoked response potentials might serve as an objective marker for cognition.

Full text access
Original article
CircRNA-miRNA-mRNA regulatory network in high-altitude hypobaric hypoxia-induced hearing impairment and hearing acclimatization
Danzeng Awang, Kanzi Danzeng, Tianheng Wang, Quzong Deji, Mengting Huang, Hailong Ren, Xinzhu Liu, Binghan Zhao, Lanzi Gongga
Highlights

  • Hearing impairment- and acclimatization-related circRNAs and genes were identified.

  • Hearing impairment and hearing acclimatization ceRNA networks were constructed.

  • Hearing impairment ceRNA networks regulated anterograde trans-synaptic signaling.

  • Hearing impairment ceRNAs regulated the negative response to growth factor stimuli.

  • Hearing acclimatization ceRNA networks regulated embryonic organ development.

Full text access
Review article
Experts' discussion: implications of the World Health Organization's World report on hearing for the cochlear implant field
Wolf-Dieter Baumgartner, Javier Gavilán, Abdelhamid Benghalem, Suela Sallavaci, Gunesh Rajan, Ranjith Rajeswaran, Mario Zernotti, Shelly Chadha
Highlights

  • Hearing loss is on the rise.

  • Low- and middle-income countries face more challenges.

  • Key challenges are access disparities and lack of reimbursement policies.

  • Hearing care should be integrated into the national primary healthcare.

  • Organizations like HEARRING can promote education and awareness.

Full text access
Original article
Effect of dupilumab on otitis media associated with eosinophilic chronic rhinosinusitis
Seiichiro Kamimura, Keisuke Ishitani, Ryota Morozumi, Eiji Kondo, Takahiro Azuma, Go Sato, Yoshiaki Kitamura
Highlights

  • Dupilumab improved EOM severity and CT scores in patients with concomitant ECRS.

  • Air-conductive hearing in EOM patients improved significantly with dupilumab.

  • Dupilumab reduced steroid use in EOM patients, suggesting long-term benefits.

  • EOM treatment has shifted significantly with dupilumab use for concomitant ECRS.

  • Dupilumab is highly effective in treating EOM, improving clinical outcomes.

Full text access
Brazilian Journal of Otorhinolaryngology (English Edition)
Announcement Nota importante
Articles submitted as of May 1, 2022, which are accepted for publication will be subject to a fee (Article Publishing Charge, APC) payment by the author or research funder to cover the costs associated with publication. By submitting the manuscript to this journal, the authors agree to these terms. All manuscripts must be submitted in English.. Os artigos submetidos a partir de 1º de maio de 2022, que forem aceitos para publicação estarão sujeitos a uma taxa (Article Publishing Charge, APC) a ser paga pelo autor para cobrir os custos associados à publicação. Ao submeterem o manuscrito a esta revista, os autores concordam com esses termos. Todos os manuscritos devem ser submetidos em inglês.