Gelsolin overexpression significantly correlated with unfavorable survival.

Increased gelsolin expression was associated with lymphovascular invasion.

Gelsolin expression was higher in patients with advanced-stage laryngeal carcinoma.

Locoregional recurrence risk is higher in cases wıth gelsoline overexpression.

Gelsolin expression could be regarded as a novel independent prognostic biomarker.

Head and neck schwannomas commonly present as a painless swelling in the neck, mostly in middle-aged females.

Contrast computed tomography and magnetic resonance images can guide the diagnosis as well as surgery.

Fine needle aspiration cytology with cellular smears is a cost-effective diagnostic tool for superficial lesions.

Complete enucleation with preservation of nerve of origin is the preferred treatment modality, with negligible recurrence.

Postoperative nerve palsy may be seen if the nerve of origin is not adequately identified or inaccessible.

In nasopharyngeal cancers, the most important therapeutic problem in treatment resistance is radiation resistance.

Minichromosome maintenance complex has a critical function in DNA replication and oncogenic signaling pathways.

In the current study, the overexpression of minichromosome maintenance complex 2, 3, 5, 6 and 7 indicated bad prognosis.

Minichromosome maintenance complex 7 was an independent prognostic factor for survival outcomes and may be a potential therapeutic target for the treatment of nasopharyngeal cancer.

Confocal laser endomicroscopy enables real-time, non-invasive identification of malignancy in pharynx and larynx.

Confocal laser endomicroscopy classification scores for the oral mucosa are also valid in pharynx and larynx.

Sensitivity and specificity for carcinoma was 81.3% and 85.5%, respectively.

Confocal laser endomicroscopy can be performed with substantial interrater agreement (k = 0.64).

Presently confocal laser endomicroscopy can aid intraoperative assessment but does not replace histology.

Partial glossectomy and reconstruction strategy influences speech and swallowing.

Patients with a higher tongue motility had better articulation and less dysphagia.

Worse functional outcomes induced a lower quality of life.

Airway management following maxillofacial microvascular reconstruction is complex.

Lack of consensus exists regarding the optimal airway management perioperatively.

Routine use of tracheostomy is unnecessary.

Tracheostomy should be considered on a case-to-case basis.

We evaluated pharyngeal leakage and fistulae using contrast CBCT.

Contrast CBCT provides three-dimensional images taken in a sitting position.

Contrast CBCT is useful for accurate diagnosis of leakage and fistula.

Contrast CBCT may be an effective option to detect pharyngeal leakage and fistulae.

Sensitivity raised by unenhanced 3-Tesla MRI with US and MIBI in hyperparathyroidism.

MRI could detect every parathyroid lesion that had been found in US.

Undetected lesions in MRI were 6 mm or less, which are size of normal parathyroid.

Fat-suppressed T2-weighted images could exhibit parathyroid lesions conspicuously.

Secondary TEP under local anesthesia generates fewer costs.

Using flexible transillumination device reduces the risk of complications.

Success rates of VP encourage its adoption in laryngectomee patients.

Prognosis of subglottic squamous cell carcinoma remained poor over the years.

Combination of surgery and adjuvant therapies improved the survival outcomes.

Early-stage tumors benefited from larynx preservation surgery; advanced tumors benefited from total laryngectomy.

Vein grafting is a reliable option for challenging head and neck reconstruction.

Vein grafting is a reliable option in free flap salvage cases.

High free flap survival rate shows vein graft reliability.

An increased postoperative complication in free flap with vein grafting is noted.

Patients with oral SCC present significant weight loss and immune compromise.

Increased values of RDW and high weight loss were risk factors for lower survival.

Patients undergoing treatment must receive a complete nutritional evaluation.

Nutritional intervention can be effective, preventing nutritional deterioration.

Radiotherapy (RT) serves as the most effective treatment for Nasopharyngeal Carcinoma (NPC) and can cause carotid stenosis.

This meta-analysis of 16 studies assessed the impact of RT on carotid stenosis in NPC patients, as well as to explore the risk factors for significant carotid stenosis.

Results showed that RT increased the risk of carotid stenosis in patients with NPC. Age, smoking habit and time interval from radiotherapy were independent predictors of significant carotid stenosis.

miR-375 is lowly expressed in LSCC cell lines.

miR-375 regulates the proliferation, migration and invasion of LSCC cells.

miR-375 targets CST1.

miR-375 inhibits proliferation of LSCC cells by targeting CST1.

Among patients with oropharyngeal squamous cell carcinoma, 86.3% had advanced-stage disease and 13.7% had early-stage disease at diagnosis.

Disease-free survival did not differ significantly between patients receiving medical and surgical treatment among patients with the same staging.

Patients receiving medical treatment had shorter overall survival in both early and advanced stages of the disease compared with those undergoing surgery.

TILs may control tumor or delay the acquiring of aggressive phenotypes.

Higher number of TILs in primary tumor tissues are associated with favorable prognosis.

Higher number of CD45RO+TILs may be an indicator of efficient anti-tumor immune responses.

CD45RO+ cells are a valuable biomarker for predicting prognosis of larynx SCC patients.

Head and neck cancer recurs more frequently in the first 2–3 years after treatment.

Early detection of recurrence events is important.

Diagnostic imaging methods are an indispensable tool in the follow up of the disease.

The post-treatment neck study is controversial.

Parotidectomy and neck dissection in locally advanced (laCSCC) and relapsed Cutaneous Squamous Cell Carcinoma (reCSCC) were evaluated.

Worst survivals were observed in T4, positive P stage and positive parotid metastasis.

The parotid metastasis was present in 50% with OR = 37.6 to evolve into positive neck metastasis.

The occult, neck metastasis and neck extracapsular spread rate was 13.5%, 51.3% and 37.8%.

We propose partial for P0 or total parotidectomy for P1-3 and neck dissection to all these patients.

Active surveillance for low risk papillary microcarcinoma is a strategy to prevent excessive early treatment, among other advantages.

Snowball sampling strategy is feasible and able in reaching hard-to-reach groups, such as doctors of different specialties, in different work environments or in large countries.

In Brazil, total thyroidectomy seems to be the most indicated treatment for thyroid papillary microcarcinoma.

The involvement of primary spaces predominated in disseminated odontogenic infections.

Laboratory tests higher values are related to greater involvement of fascial spaces.

Greater hospitalization stays are related to greater involvement of fascial spaces.

Intensive care unit admission is related to greater involvement of fascial spaces.

80% of the patients with osteolipoma presented with a painless mass which had pre-existed for at least 4-months contrary to a lump associated with a malignant process.

Histology consisting of variable mixture of adipose tissue interspersed with lamellar bone, woven bone, cancellous bone, compact bone and osteoblasts is key to confirm the diagnosis of osteolipoma.

Osteolipoma should not be confused with other benign tumours with bony element including parosteal lipomas and intraosseous lipomas.

Recognising osteolipoma early is important for patient reassurance as well as avoiding unnecessary radical treatment.