NKX2-1 gene is an emerging target for H19 lncRNA.

Binding site of H19 with NKX2-1 overlaps with has-miR-1827.

Increased expression of NKX2-1 observed in benign nodular goiter.

PNN resection & hormone transnasal nebulization shows good efficacy on DTRS.

Combination can relieve the symptoms of DTRS patients, reduce adverse reactions.

The combination deserves a promotion in clinical practice.

Hearing loss children with multiple disabilities benefits from cochlear implantation.

Communications improved with increasing duration of device usage.

Cochlear implant is beneficial in reducing family’s stress level.

The chronic rhinosinusitis patients with chronic cough had significant obstructive lung function.

The SNOT score is high in chronic cough patients with chronic rhinosinusitis.

The lower airway examination is important in chronic cough patients.

Adhesive bone conduction device elicits improvement in speech perception.

Adhesive bone conduction do not improve sound localisation abilities.

Adhesive bone conduction is useful to children with single-sided deafness.

Elderly presented moderate swallowing impairment for consistencies.

There was no difference between clinical and instrumental evaluation.

The assessment of swallowing in the elderly must consider physiological changes.

Minor complications related with vestibular system were more common.

Major complications: changes of wound, device failure and electrode extrusion.

Children with a mean age of 19.3-months are more susceptible to infections.

There was no correlation between advanced age and higher complication rates.

Age should not be an exclusion factor.

Endoscopic thyroidectomy through chest-collarbone approach is safe and feasible.

Chest-collarbone endoscopic thyroid surgery improves in a good cosmetic outcome.

Preoperative evaluation of nodule size and nature affects the success rate of surgery.

The expression level of EPHX4 was higher in HNSC patients’ tissues.

EPHX4 expression is closely associated with the immunity of HNSC.

EPHX4 promotes HNSC cells proliferation, colony formation and invasion.

Lung impairment due to COVID-19 increases the voice handicap index score.

The voice-related quality of life score is reduced in these patients.

There is a correlation between pulmonary function and the changes in voice.

Video laryngoscopy did not identify any laryngeal changes in these patients.

SSNHL patients had a higher risk of concomitant hypertension and elevated atherosclerogenic lipid levels.

APOB, APOE, and LCI were identified as independent risk factors.

Certain lipids showed a positive linear correlation with hearing loss.

When TC was in borderline high range, the treatment effect was the best.

Post-extubation laryngitis was confirmed in the majority of suspected cases.

Bedside nasopharyngolaryngoscopy assisted, but over half required microlaryngoscopy.

Laryngeal stenosis is associated with lesion severity and extubation failures.

Close follow-up after discharge prevented any additional tracheostomies.

Prognosis is influenced by comorbidities, lesion severity, and tracheostomy.

We searched PubMed, Embase and Cochrane Library databases.

This study included 22 randomized controlled trials with a total of 2354 patients.

Acoustic therapy combined with cognitive behavior can treat chronic tinnitus.

Non-antibiotic antimicrobial therapies offer potential alternatives in CRS patients.

Most non-antibiotic antimicrobial therapies did not show important side effects.

The majority of studies reviewed have low level of evidence.