Journal Information
Vol. 90. Issue 2.
(March - April 2024)
Chronic rhinosinusitis with nasal polyps: changing expectations
Otavio B. Piltcher
Braz J Otorhinolaryngol. 2024;90:101415
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Original articles
Exploring the impact of inflammatory endotypes on olfactory function and quality of life in chronic rhinosinusitis patients
Nájla Nonis Zucoloto, Felipe Silva de Aguiar, Natália Medeiros Dias Lopes, Ellen Cristine Duarte Garcia, Fabrizio Ricci Romano, Thiago Freire Pinto Bezerra, Wilma Terezinha Anselmo Lima, Marco Aurélio Fornazieri
Braz J Otorhinolaryngol. 2024;90:101364

  • Type 2 Chronic Rhinosinusitis (CRS) had more severe disease.

  • Type 2 CRS had worse olfactory function.

  • Type 2 CRS had lower quality of life.

  • Type 2 CRS presented higher Lund-Mackay and Lund-Kennedy scores than non-type 2.

  • Furthermore, type 2 CRS had a higher prevalence of nasal polyps, asthma, and NERD.

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Utility of a clinical risk scale to predict the requirement of advanced airway management in patients with a diagnosis of deep neck abscess
Juan Carlos Méndez Gutiérrez, Luis García-Covarrubias, Arturo Reding-Bernal, Héctor A. Velázquez Chong, Diana F. Fernández Ángel, Aldo García Covarrubias, Juan Carlos Hernández-Rivera
Braz J Otorhinolaryngol. 2024;90:101360

  • Deep neck abscesses are one of the most dangerous emergencies in otolaryngology.

  • The principal complication in deep neck abscesses is airway obstruction.

  • It is difficult to predict which patients will require Advance Airway Management.

  • Some factors have been used to create scales to stratify the risk of complications.

  • The benefit of a risk scale is to prevent requirement of advanced airway management.

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Effects of Metabolic Syndrome and its components on the postoperative recurrence in Chronic Rhinosinusitis with Nasal Polyps’ patients
Yu Chen, Tiansheng Wang, Ru Gao, Fengjun Wang
Braz J Otorhinolaryngol. 2024;90:101371

  • MetS increased the risk of postoperative recurrence in CRSwNP.

  • Recurrence risk increases with an increasing number of components.

  • Allergic rhinitis as a potential risk factor for CRSwNP recurrence.

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Aeroallergen sensitization patterns among patients with chronic rhinitis with or without concomitant asthma
Tássia Milenna Oliveira de Souza, Jamille Souza Fernandes, Cinthia Vila Nova Santana, Marcus Miranda Lessa, Álvaro A. Cruz
Braz J Otorhinolaryngol. 2024;90:101351

  • The chance of asthma in polysensitization individuals is increased.

  • Allergic rhinitis is a relevant and independent risk factor for asthma development.

  • Lower airway obstruction should be evaluated in patients with chronic rhinitis.

  • Polysensitization and asthma are associated in a low-income setting in Brazil.

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Significance of radiologic extranodal extension in locoregionally advanced nasopharyngeal carcinoma with lymph node metastasis: a comprehensive nomogram
Jianming Ding, Jiawei Chen, Yuhao Lin, Jiabiao Hong, Chaoxiong Huang, Zhaodong Fei, Chuanben Chen
Braz J Otorhinolaryngol. 2024;90:101363

  • Large-case study showed poor survival in cancer with radiologic extranodal extension.

  • New predictor for nasopharyngeal cancer survival via radiologic extranodal extension.

  • Predictive tool outperformed 8th TNM staging in accuracy and discriminative ability.

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Postoperative effects of bilateral sphenopalatine ganglion blockade in septorhinoplasty operations; double-blind randomized clinical trial
Erhan Gökçek, Gunay Kozan
Braz J Otorhinolaryngol. 2024;90:101373

  • Sphenopalatine ganglion blockade was very effective in postoperative pain control after septorhinoplasty operations.

  • Sphenopalatine ganglion blockade resulted in less analgesic drug consumption after septorhinoplasty operations.

  • Sphenopalatine ganglion blockade was not effective in postoperative nausea and vomiting after septorhinoplasty operations.

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Surgical treatment and prognosis of recurrent and radiotherapy insensitive nasopharyngeal carcinoma
Yanming Zhao, Jugao Fang, Qi Zhong, Jiamin Zhang, Jiaming Chen, Lizhen Hou, Ru Wang
Braz J Otorhinolaryngol. 2024;90:101366

  • The treatment of recurrent or some pathological types of NPC is full of challenges.

  • The surgical treatment has a good therapeutic effect on NPC.

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Facial soft tissue changes and volumetric analysis of upper airways in patients undergoing surgically assisted rapid maxillary expansion using a transpalatal distractor
Carlos Augusto de Jesus Oliveira Gonçalves, João de Jesus Viana Pinheiro, Marcelo Newton Carneiro, Ana Karla da Silva Tabosa, Roberto Carlos Rivadeneira Cárdenas, José Thiers Carneiro
Braz J Otorhinolaryngol. 2024;90:101372

  • Changes were observed in the angular measurements (nasolabial angle).

  • Changes were observed in the facial soft tissue (nasal width and alar base).

  • Airway volumetric increase after SARME.

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Development of a mobile app for the evaluation of patients with chronic rhinosinusitis
Priscila Novaes Ferraiolo, Sergio Duarte Dortas, Fabiana Chagas da Cruz, Priscilla Campos de Souza Ramos, José Elabras Filho, Marise da Penha Costa Marques, Cláudia Maria Valete-Rosalino
Braz J Otorhinolaryngol. 2024;90:101375

  • Patients with chronic rhinosinusitis are a heterogeneous group.

  • There are regional diferences of patients with chronic rhinosinusitis.

  • Chronic rhinosinusitis international guidelines are not unanimous.

  • An expert consensus can standardize the care of these patients.

  • The creation of a mobile application make the expert consensus more accessible to use.

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Clinical diagnoses of patients showing caloric inversion
Hansol Kim, Haeun Souh, Dong-Han Lee, Jung Eun Shin, Chang-Hee Kim
Braz J Otorhinolaryngol. 2024;90:101378

  • Caloric inversion was observed in 0.29% of patients who underwent caloric tests.

  • Caloric inversion can be observed in various diseases without TM perforation.

  • Clinicians should be careful in interpreting caloric tests in dizzy patients.

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Evaluation of inner ear damage by mastoid drilling with measurement of serum prestin (SLC26A5) levels
Ayca Baskadem Yilmazer, Onur Tanrısever, Maide Hacer Alagoz, Rasim Yilmazer, Ayse Enise Goker, Belgin Tutar, Yavuz Uyar
Braz J Otorhinolaryngol. 2024;90:101380

  • Mastoid drilling is not related to a significant inner ear injury.

  • Suction and ossicular manipulation trauma can increase serum prestin levels.

  • Suction trauma can cause sensorineural hearing loss at 2000 and 4000 Hz.

  • Ossicular manipulation trauma can cause sensorineural hearing loss at 2000 and 4000 Hz.

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One simple question detects motion sickness susceptibility in migraine patients
Gülden Akdal, Pınar Özçelik, Birgül Balcı, Gábor Michael Halmágyi, Belgin Ünal
Braz J Otorhinolaryngol. 2024;90:101382

  • Motion sickness is very common in patients with vestibular migraine.

  • Motion sickness questionnaires are time-consuming for patient and doctor.

  • A positive answer to just one simple question gives comparable results.

  • The question: While riding in a car or bus, can you read without getting motion sick?

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Detailed analysis of inner ear malformations in CHARGE syndrome patients – correlation with audiological results and proposal for computed tomography scans evaluation methodology
Agata Szleper, Magdalena Lachowska, Tomasz Wojciechowski, Katarzyna Pronicka-Iwanicka
Braz J Otorhinolaryngol. 2024;90:101383
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Effective prognostic risk model with cuproptosis-related genes in laryngeal cancer
Cong Li, Yongzhi Zhu, Song Shi
Braz J Otorhinolaryngol. 2024;90:101384

  • Cuproptosis genes stratified laryngeal cancer into diverse prognostic subtypes.

  • TMEM2, DACT1, STMN2, and GPR173 form our prognostic model.

  • TMEM2, DACT1, STMN2, GPR173 shape the risk model.

  • High-risk samples upregulated angiogenesis, EMT, and KRAS pathways.

  • Clinical_M, Clinical_cN, risk groups predict laryngeal cancer prognosis.

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Deficiency in infiltration of CD8/CD3 positive lymphocytes and macrophages plays a role in lip carcinogenesis: an immunohistochemical study
Iana Aragão Magalhães, Gabriella Alves Juliao Costa, Marcela Maria Fontes Borges, Anna Clara Aragão Matos Carlos, Karine Cestaro Mesquita, Larissa Mont´Alverne de Arruda, Maria do Perpétuo Socorro Saldanha Cunha, Fabrício Bitu Sousa, Paulo Goberlânio de Barros Silva
Braz J Otorhinolaryngol. 2024;90:101379

  • Macrophages (CD68+) migrate into the tumor and interact with CD3, CD8 and CD20.

  • CD20 affects perineural invasion and histological gradation.

  • More aggressive tumors have lower amounts of CD20.

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Nasal polyps show decreased mucociliary transport despite vigorous ciliary beating
Thi Nga Nguyen, Yuma Koga, Tetsuro Wakasugi, Takuro Kitamura, Hideaki Suzuki
Braz J Otorhinolaryngol. 2024;90:101377

  • Mucociliary transport velocity of nasal polyps was lower than that of turbinates.

  • Ciliary beat frequency did not differ between the two tissues.

  • Expression of Planar Cell Polarity (PCP) proteins was decreased in nasal polyps.

  • Lowered mucociliary transport in nasal polyps may be due to disarranged PCP.

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Anlotinib suppressed tumor cell proliferation and migration in hypopharyngeal carcinoma
Hao Song, Qing Song, Xiangkun Zhao, Yuteng Yang, Yakui Mou, Yumei Li, Xicheng Song
Braz J Otorhinolaryngol. 2024;90:101397

  • Anlotinib inhibits the proliferation of Fadu cells in hypopharyngeal carcinoma.

  • Anlotinib blocks G2/M and promotes apoptosis in the hypopharyngeal cancer cell cycle.

  • Anlotinib puts Fadu cells in a hypoxic state, which in turn inhibits cell proliferation.

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Review articles
Surgical safety and effectiveness of bilateral axillo-breast approach robotic thyroidectomy: a systematic review and meta-analysis
Yun Jin Kang, Gulnaz Stybayeva, Se Hwan Hwang
Braz J Otorhinolaryngol. 2024;90:101376

  • Bilateral Axillo-Breast Approach Robotic Thyroidectomy (BABART) has been developed.

  • We directly compare BABART with other approaches in outcomes and complications.

  • BABART's operation time, drainage, and cosmetic satisfaction were insufficient.

  • However, the surgical performance of BABART was not inferior.

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Case reports
The application of myofascial anterolateral thigh flap in reconstruction of oropharyngeal defect: a case report
Shengyou Ge, Xiaochen Yang, Zongxuan He, Wei Shang, Kai Song
Braz J Otorhinolaryngol. 2024;90:101367
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Necrotizing sialometaplasia on the hard palate after sequential induced vomiting: case study
Elaine Costa, Gabriel Caetano de Jesus, Bruno Siqueira Bellini, Ana Cristina Coelho Dal Rio Teixeira
Braz J Otorhinolaryngol. 2024;90:101385
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Brazilian Journal of Otorhinolaryngology (English Edition)
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